A common problem with right hand guitar technique involves picking ’in between’ two strings. Playing a downstroke on a lower string followed by an upstroke on a higher string is easy enough, but when you reverse the picking direction it becomes more difficult. Here is an example using open strings.
Once you are comfortable with the previous exercise, try the following 16th note patterns which make use of "inside" picking. Make sure you start with a downstroke and use strict alternate picking throughout. Once again, use a metronome and take them slowly at first.
This lick features the frequent use of slurs.
It is common to use sixteenth notes leading up to a bend.
Here is a riff based on sixteenth notes. In this example, every note is picked. Use alternate picking and practice it with a metronome to keep your timing solid. Take it slowly until you can play it perfectly and then gradually increase the tempo.